Cool.
Disabled output variables do not defuzzify.
Disabled Input variables do not activate antecedents in the rules (see https://github.com/fuzzylite/fuzzylite/blob/release/fuzzylite/src/rule/Antecedent.cpp#L72).
There are no limits on numbers of rules. Personally, I find more than 100 rules to be really hard to trace the correctness of the model. Perhaps you may want to split the model into different controllers and cascade them.
Cheers.